⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873887 | 0.77 | — | — | |
| SCHEMBL1274491 | 0.73 | — | — | |
| SCHEMBL4240251 | 0.69 | EPHX1 (0.41) | — | |
| SCHEMBL5305973 | 0.69 | — | — | |
| SCHEMBL1274764 | 0.69 | — | — | |
| SCHEMBL8000387 | 0.69 | — | — | |
| SCHEMBL10533982 | 0.69 | — | — | |
| SCHEMBL8012547 | 0.69 | — | — | |
| SCHEMBL1809056 | 0.69 | — | — | |
| SCHEMBL5650410 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650827-B | Preparation method, intermediate compound and synthesis method for anthracycline derivatives | 戊言医药科技（上海）有限公司 | 2024-03-15 | — | — | CN | claimed |
| EP-3543355-B1 | METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF P13K/AKT/MTOR INHIBITOR ON BASIS OF PHLDA1 OR PIK3C2B EXPRESSION | TAIHO PHARMACEUTICAL CO LTD (JP) | 2020-12-23 | — | — | EP | claimed |
| EP-3012327-B1 | METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF PI3K/AKT/mTOR INHIBITOR ON BASIS OF PHLDA1 OR PIK3C2B EXPRESSION | TAIHO PHARMACEUTICAL CO LTD (JP) | 2020-12-16 | — | — | EP | claimed |
| EP-3543355-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF P13K/AKT/MTOR INHIBITOR ON BASIS OF PHLDA1 OR PIK3C2B EXPRESSION | Taiho Pharmaceutical Co., Ltd. (JP) | 2019-09-25 | — | — | EP | claimed |
| US-10155990-B2 | Method for predicting therapeutic efficacy of PI3K/AKT/mTOR inhibitor on basis of PHLDA1 or PIK3C2B expression | Taiho Pharmaceuticals, Inc. (JP) | 2018-12-18 | — | — | US | claimed |
| EP-2868660-B1 | ANTITUMOR EFFECT POTENTIATOR COMPRISING AN IMIDAZOOXAZINE COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2017-12-27 | — | — | EP | claimed |
| US-9375434-B2 | Antitumor effect potentiator composed of imidazooxazine compound | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2016-06-28 | — | — | US | claimed |
| EP-3012327-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF PI3K/AKT/mTOR INHIBITOR ON BASIS OF PHLDA1 OR PIK3C2B EXPRESSION | Taiho Pharmaceutical Co., Ltd. (JP) | 2016-04-27 | — | — | EP | claimed |
| US-20160102366-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFICACY OF PI3K/AKT/mTOR INHIBITOR ON BASIS OF PHLDA1 OR PIK3C2B EXPRESSION | TAIHO PHARMACEITUCAL CO., LTD. (JP) | 2016-04-14 | — | — | US | claimed |
| US-9289431-B2 | — | — | 2016-03-22 | — | — | US | claimed |
| WO-2008100621-A2 | TETRAHYDRO-PYRAZOLO-PYRIDINE THIOETHER MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | claimed |
| WO-2008100635-A1 | 1- [3- (MONOCYCLIC AMINO) PROPYL] - 4, 5, 6, 7-TETRAHYDRO-1H-PYRAZOLO [4, 3-C] -PYRIDINES AS MODULATORS OF CATHEPSIN S | SUNESIS PHARMACEUTICALS, INC. (US) | 2008-08-21 | — | — | WO | claimed |
| WO-2008008747-A1 | [4,5']BIPYRIMIDINYL-6,4'-DIAMINE DERIVATIVES AS PROTEIN KINASE INHBITORS | IRM LLC (BM) | 2008-01-17 | — | — | WO | claimed |
| EP-1841752-A1 | 3,4-DIHYDRO-2-NAPHTHAMIDE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2007-10-10 | — | — | EP | claimed |
| WO-2006077487-A1 | 3,4-DIHYDRO-2-NAPHTHAMIDE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2006-07-27 | — | — | WO | claimed |
| EP-1683790-A1 | 3,4-dihydro-2-naphthamide derivatives as selective dopamine D3 ligands | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2006-07-26 | — | — | EP | claimed |
| EP-1073428-B1 | DIHYDROXYPHENYL DERIVATIVES FOR HEPATOPROTECTION AND TREATMENT OF LIVER DISEASES | CHOONGWAE PHARMA CO LTD (KR) | 2004-10-27 | — | — | EP | claimed |
| EP-0836595-B1 | TRIAZOLINE AND ISOXAZOLINE BIS-OXIME DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2004-01-02 | — | — | EP | claimed |
| EP-0280240-B1 | Cephalosporin derivatives, process for their preparation and antibacterial agents | BANYU PHARMA CO LTD (JP) | 1994-09-14 | — | — | EP | claimed |
| US-4160021-A | ANTIALLERGENS, ANTIHISTAMINES | SMITHKLINE CORPORATION (US) | 1979-07-03 | — | — | US | claimed |