SCHEMBL8968294

SCHEMBL8968294

C=CCOc1ccc(-c2ccc(-c3ccc(C4=CCC(C5CCC(CCCCCC)CC5)CC4)c(F)c3F)cc2)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 3/20 0.32
HTR2A P28223 2/20 0.32
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8969050 1.00 HTR2C (0.32) HTR2CHTR2AHTR2B
SCHEMBL8968130 0.96 HTR2C (0.33) HTR2CHTR2AHTR2B
SCHEMBL8965971 0.94 HTR2C (0.30) HTR2CHTR2B
SCHEMBL8964281 0.93
SCHEMBL8965745 0.93 HTR2C (0.31) HTR2CHTR2AHTR2B
SCHEMBL8968945 0.92
SCHEMBL8964118 0.92
SCHEMBL8967614 0.91
SCHEMBL8968989 0.91
SCHEMBL8967694 0.90 AVPR2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed