Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 3/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.64 |
| ▸ | PPP1CC | P36873 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080046 | 0.81 | PPM1B (0.84) | PPM1BPTPN1PPP1CCKDM4EGMNN | |
| SCHEMBL6549231 | 0.79 | TFPI2 (0.48) | PPM1BPTPN1PPP1CCKDM4EGMNN | |
| SCHEMBL390763 | 0.78 | PPM1B (1.00) | PPM1BPTPN1PPP1CCKDM4EGMNN | |
| SCHEMBL15590874 | 0.78 | PPM1B (1.00) | PPM1BPTPN1PPP1CCKDM4EGMNN | |
| SCHEMBL8758857 | 0.78 | PPM1B (1.00) | PPM1BPTPN1PPP1CCKDM4EGMNN | |
| SCHEMBL2332679 | 0.78 | PPM1B (1.00) | PPM1BPTPN1PPP1CCKDM4EGMNN | |
| SCHEMBL9460572 | 0.78 | PPM1B (1.00) | PPM1BPTPN1PPP1CCKDM4EGMNN | |
| SCHEMBL26613051 | 0.78 | PPM1B (1.00) | PPM1BPTPN1PPP1CCKDM4EGMNN | |
| SCHEMBL25641810 | 0.77 | PPM1B (0.56) | PPM1BPTPN1PPP1CCKDM4EGMNN | |
| SCHEMBL18235530 | 0.74 | PPM1B (0.72) | PPM1BPTPN1PPP1CCKDM4EGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470469-B1 | 2-Oxa-3-alkoxy-7-hydroxy-bicyclo[2.2.1]heptanes | BASF AG (DE) | 1996-03-13 | — | — | EP | disclosed |