Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969607 | 0.83 | KDM4E (0.31) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL8969583 | 0.81 | KDM4E (0.30) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL8969718 | 0.78 | KDM4E (0.30) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL8969659 | 0.76 | — | — | |
| SCHEMBL8968914 | 0.76 | — | — | |
| SCHEMBL8968365 | 0.76 | — | — | |
| SCHEMBL8969545 | 0.75 | KDM4E (0.34) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL8969611 | 0.72 | PDE3B (0.32) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL8969217 | 0.72 | PDE3B (0.43) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL8969297 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |