Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.68 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246063 | 0.94 | CYP4F2 (0.76) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11410892 | 0.88 | CYP4F2 (0.68) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7722448 | 0.84 | CYP4F2 (0.70) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL69660 | 0.84 | CYP4F2 (0.86) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL1859513 | 0.83 | CYP4F2 (0.78) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13948404 | 0.82 | CYP4F2 (0.73) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8567928 | 0.82 | CYP4F2 (0.63) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL490584 | 0.81 | IAPP (0.64) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL16318789 | 0.81 | CYP4F2 (0.62) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL14360800 | 0.81 | CYP4F2 (0.58) | CYP4F2CYP4A11ALDH1A1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |