Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 3/20 | 0.81 |
| ▸ | MMP13 | P45452 | 11/20 | 0.49 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968548 | 0.90 | FDFT1 (0.68) | FDFT1MMP13MMP2 | |
| SCHEMBL8968715 | 0.90 | FDFT1 (1.00) | FDFT1MMP13MMP2 | |
| SCHEMBL8969801 | 0.88 | FDFT1 (0.74) | FDFT1MMP13MMP2 | |
| SCHEMBL8421721 | 0.86 | FDFT1 (0.74) | FDFT1MMP13MMP2 | |
| SCHEMBL8970179 | 0.81 | FDFT1 (0.85) | FDFT1MMP13MMP2 | |
| SCHEMBL8969498 | 0.81 | FDFT1 (0.55) | FDFT1MMP13MMP2 | |
| SCHEMBL27486671 | 0.81 | FDFT1 (0.83) | FDFT1MMP13MMP2 | |
| SCHEMBL27501580 | 0.80 | FDFT1 (0.84) | FDFT1MMP13MMP2 | |
| SCHEMBL9432075 | 0.80 | FDFT1 (0.84) | FDFT1MMP13MMP2 | |
| SCHEMBL8968858 | 0.78 | FDFT1 (0.80) | FDFT1MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121718-A | Heterocyclic derivatives | ZENECA LTD (GB) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696284-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025459-A1 | HETEROCYCLIC DERIVATIVES | ZENECA LIMITED (GB) | 1994-11-10 | — | — | WO | disclosed |