Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.80 |
| ▸ | ACHE | P22303 | 2/20 | 0.80 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.42 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | GJB2 | P29033 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL8992146 | 0.99 | BCHE (0.78) | BCHEACHEMAN2A1MAN1B1PDE4D | |
| SCHEMBL29448049 | 0.89 | BCHE (1.00) | BCHEACHEPDE4DLMNAPDPK1 | |
| SCHEMBL20680384 | 0.89 | BCHE (1.00) | BCHEACHEPDE4DLMNAPDPK1 | |
| SCHEMBL8715953 | 0.89 | BCHE (0.94) | BCHEACHEPDE4DLMNAPDPK1 | |
| SCHEMBL13777996 | 0.89 | BCHE (1.00) | BCHEACHEPDE4DLMNAPDPK1 | |
| SCHEMBL11464350 | 0.89 | BCHE (1.00) | BCHEACHEPDE4DLMNAPDPK1 | |
| SCHEMBL10444884 | 0.89 | BCHE (0.94) | BCHEACHEPDE4DLMNAPDPK1 | |
| SCHEMBL31103765 | 0.89 | BCHE (1.00) | BCHEACHEPDE4DLMNAPDPK1 | |
| SCHEMBL12164680 | 0.89 | BCHE (0.94) | BCHEACHEPDE4DLMNAPDPK1 | |
| SCHEMBL6251358 | 0.89 | BCHE (0.94) | BCHEACHEPDE4DLMNAPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5086072-A | — | — | None | — | — | JP | disclosed |
| US-5536732-A | REDUCING INFECTIOUSNESS OF HIV | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-16 | — | — | US | disclosed |
| US-5504078-A | α-glucosidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0454580-B1 | Novel nojirimycin derivatives | MERRELL DOW PHARMA (US) | 1995-12-27 | — | — | EP | disclosed |
| EP-0532668-B1 | NOVEL ALPHA-GLUCOSIDASE INHIBITORS | MERRELL DOW PHARMA (US) | 1995-11-15 | — | — | EP | disclosed |
| EP-0345104-B1 | Novel Alpha-glucosidase inhibitors | MERRELL DOW PHARMA (US) | 1995-11-02 | — | — | EP | disclosed |
| US-5252587-A | Viricides, aids therapy, antidiabetic agent | MERRELL DOW PHARMACEUTICALS, INC. (US) | 1993-10-12 | — | — | US | disclosed |
| JP-H0586072-A | NEW NOJIRIMYCIN DERIVATIVE | MERRELL DOW PHARMACEUT INC | 1993-04-06 | — | — | JP | disclosed |
| EP-0532668-A1 | NOVEL -g(a)-GLUCOSIDASE INHIBITORS. | MERRELL DOW PHARMA (US) | 1993-03-24 | — | — | EP | disclosed |
| US-5157116-A | Antidiabetic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-10-20 | — | — | US | disclosed |
| WO-1991018915-A1 | NOVEL α-GLUCOSIDASE INHIBITORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-12-12 | — | — | WO | disclosed |
| EP-0454580-A2 | Novel nojirimycin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0453692-A1 | Novel nojirimycin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-30 | — | — | EP | disclosed |
| EP-0344383-A1 | Novel alpha-Glucosidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-12-06 | — | — | EP | disclosed |
| EP-0345104-A2 | Novel Alpha-glucosidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-12-06 | — | — | EP | disclosed |