Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | EP300 | Q09472 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969700 | 1.00 | KDM1A (0.41) | KDM1AEP300KDM4EHCRTR2GABRA5 | |
| SCHEMBL1390734 | 0.91 | KDM1A (0.47) | KDM1AEP300KDM4EHCRTR2GABRA5 | |
| SCHEMBL20775355 | 0.84 | KDM1A (0.45) | KDM1AEP300KDM4EHCRTR2GABRA5 | |
| SCHEMBL1929309 | 0.84 | KDM1A (0.45) | KDM1AEP300KDM4EGABRA5NPC1 | |
| SCHEMBL15632943 | 0.81 | IDO1 (0.40) | KDM1AEP300KDM4EGABRA5DGAT1 | |
| SCHEMBL23012782 | 0.81 | ATM (0.42) | KDM1AEP300 | |
| SCHEMBL17050466 | 0.81 | ACACB (0.46) | KDM1AEP300ACACB | |
| SCHEMBL20775288 | 0.80 | KDM1A (0.42) | KDM1AEP300GABRA5 | |
| SCHEMBL16758280 | 0.80 | EP300 (0.61) | KDM1AEP300 | |
| SCHEMBL8970555 | 0.79 | EP300 (0.49) | KDM1AEP300KDM4EACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445257-B1 | PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5204477-A | PYRIDINE DERIVATIVES IN LIQUID CRYSTALLINE MEDIUM USEFUL FOR ELECTROOPTICAL DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0445257-A1 | PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |
| WO-1991004249-A1 | PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |