Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2111739 | 0.93 | TYMP (0.48) | TYMPADORA2AADORA2BSLC29A1ADORA1 | |
| SCHEMBL5580213 | 0.84 | ADORA1 (0.57) | TYMPADORA2BADORA1ADORA3PRMT5 | |
| SCHEMBL9096320 | 0.84 | TYMP (0.56) | TYMPADORA2AADORA2BSLC29A1ADORA1 | |
| SCHEMBL2111737 | 0.82 | PRMT5 (0.45) | TYMPSLC29A1ADORA1PRMT5WDR77 | |
| SCHEMBL15954506 | 0.82 | TYMP (0.40) | TYMPADORA2AADORA2BSLC29A1ADORA1 | |
| SCHEMBL6394670 | 0.80 | ADORA1 (0.48) | TYMPADORA1PRMT5WDR77 | |
| SCHEMBL2115367 | 0.80 | ADORA2A (0.55) | ADORA2AADORA2BADORA1ADORA3PRKAG1 | |
| SCHEMBL8970099 | 0.79 | TYMP (0.34) | TYMPADORA2AADORA2BSLC29A1ADORA1 | |
| SCHEMBL439196 | 0.79 | ADORA2A (0.54) | ADORA2AADORA2BADORA1ADORA3PRKAG1 | |
| SCHEMBL30901148 | 0.79 | ADORA2A (0.54) | ADORA2AADORA2BADORA1ADORA3PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525719-A | N-protected-2'-O-methyl-and N-protected-3'-O-methyl-ribonucleosides and their phosphoramidite derivatives | CHEMGENES CORPORATION (US) | 1996-06-11 | — | — | US | disclosed |
| US-5525719-A | N-protected-2'-O-methyl-and N-protected-3'-O-methyl-ribonucleosides and their phosphoramidite derivatives | CHEMGENES CORPORATION (US) | 1996-06-11 | — | — | US | disclosed |