Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 16/20 | 0.90 |
| ▸ | GBA1 | P04062 | 7/20 | 0.90 |
| ▸ | GAA | P10253 | 3/20 | 0.90 |
| ▸ | UGCG | Q16739 | 2/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436236 | 1.00 | GBA2 (0.90) | GBA2GBA1GAAUGCG | |
| SCHEMBL8969848 | 1.00 | GBA2 (0.90) | GBA2GBA1GAAUGCG | |
| SCHEMBL8969964 | 1.00 | GBA2 (0.90) | GBA2GBA1GAAUGCG | |
| SCHEMBL8969159 | 1.00 | GBA2 (0.90) | GBA2GBA1GAAUGCG | |
| SCHEMBL8969137 | 0.98 | GBA2 (0.90) | GBA2GBA1GAAUGCG | |
| SCHEMBL6821239 | 0.95 | GBA2 (1.00) | GBA2GBA1GAAUGCG | |
| SCHEMBL2268575 | 0.95 | GBA2 (1.00) | GBA2GBA1GAAUGCG | |
| SCHEMBL13253278 | 0.95 | GBA2 (1.00) | GBA2GBA1GAAUGCG | |
| SCHEMBL17243607 | 0.95 | GBA2 (1.00) | GBA2GBA1GAAUGCG | |
| SCHEMBL3020875 | 0.95 | GBA2 (1.00) | GBA2GBA1GAAUGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367747-B1 | Dideoxy-L-arabinitol derivatives as antiviral compounds | SEARLE & CO (US) | 1996-03-13 | — | — | EP | disclosed |
| US-4937357-A | ACYLATED DERIVATIVES OF 1,4-DIDEOXY-1,4-IMINO-L-ARABINOL | G. D. SEARLE & CO. (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0367747-A2 | Dideoxy-L-arabinitol derivatives as antiviral compounds | G.D. Searle & Co. (US) | 1990-05-09 | — | — | EP | disclosed |