Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 13/20 | 0.49 |
| ▸ | GBA1 | P04062 | 4/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964904 | 0.94 | GBA1 (0.49) | PRKCQGBA1PRKCAPRKCDSCD | |
| SCHEMBL8970244 | 0.86 | PRKCQ (0.51) | PRKCQGBA1PRKCAPRKCDMEN1 | |
| SCHEMBL8969884 | 0.85 | PRKCQ (0.53) | PRKCQPRKCAPRKCD | |
| SCHEMBL8970034 | 0.85 | PRKCQ (0.49) | PRKCQPRKCAPRKCD | |
| SCHEMBL1481538 | 0.83 | CKS1B (0.52) | PRKCQPRKCAPRKCD | |
| SCHEMBL1481470 | 0.83 | PRKCQ (0.49) | PRKCQPRKCAPRKCD | |
| SCHEMBL8969876 | 0.81 | PRKCQ (0.53) | PRKCQPRKCAPRKCD | |
| SCHEMBL9010401 | 0.81 | PRKCQ (0.53) | PRKCQPRKCAPRKCD | |
| SCHEMBL8970028 | 0.80 | PRKCQ (0.71) | PRKCQPRKCAPRKCD | |
| SCHEMBL8969734 | 0.80 | PRKCQ (0.55) | PRKCQPRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188071-B2 | Amino substituted pyridines as potent kinase inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-05-29 | — | — | US | disclosed |