Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970521 | 1.00 | GBA1 (0.48) | GBA1ALDH1A1TDP1EPHX2SPHK2 | |
| SCHEMBL11187287 | 1.00 | GBA1 (0.48) | GBA1ALDH1A1TDP1EPHX2SPHK2 | |
| SCHEMBL8970651 | 1.00 | GBA1 (0.48) | GBA1ALDH1A1TDP1EPHX2SPHK2 | |
| SCHEMBL8970667 | 1.00 | GBA1 (0.48) | GBA1ALDH1A1TDP1EPHX2SPHK2 | |
| SCHEMBL8969403 | 1.00 | GBA1 (0.48) | GBA1ALDH1A1TDP1EPHX2SPHK2 | |
| SCHEMBL8970146 | 0.98 | GBA1 (0.46) | GBA1ALDH1A1TDP1EPHX2SPHK2 | |
| SCHEMBL17384324 | 0.92 | GBA1 (0.38) | GBA1ALDH1A1TDP1EPHX2SPHK2 | |
| SCHEMBL17384323 | 0.92 | GBA1 (0.38) | GBA1ALDH1A1TDP1EPHX2SPHK2 | |
| SCHEMBL8970189 | 0.92 | GBA1 (0.38) | GBA1ALDH1A1TDP1EPHX2SPHK2 | |
| SCHEMBL13954685 | 0.89 | GBA1 (0.46) | GBA1EPHX2NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |