Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969280 | 1.00 | BTK (0.36) | BTKEPHX1MEN1BLMKMT2A | |
| SCHEMBL8969074 | 0.98 | BTK (0.37) | BTKEPHX1MEN1BLMKMT2A | |
| SCHEMBL8970591 | 0.94 | BTK (0.40) | BTKEPHX1MEN1BLMKMT2A | |
| SCHEMBL8969963 | 0.78 | CYP2C19 (0.38) | MEN1BLMKMT2ACYP2C19KDM4E | |
| SCHEMBL8970358 | 0.78 | CYP2C19 (0.38) | MEN1BLMKMT2ACYP2C19KDM4E | |
| SCHEMBL31332688 | 0.75 | GRM2 (0.41) | BTKMEN1KMT2ACYP2C19KDM4E | |
| SCHEMBL8072246 | 0.75 | CYP2C19 (0.39) | MEN1BLMKMT2ACYP2C19KDM4E | |
| SCHEMBL8970243 | 0.75 | CYP2C19 (0.39) | MEN1BLMKMT2ACYP2C19KDM4E | |
| SCHEMBL22323896 | 0.74 | SLC18A3 (0.41) | MEN1BLMKMT2AKDM4EHTT | |
| Hydrochloric Acid SCHEMBL8970750 | 0.74 | PEPD (0.39) | MEN1BLMKMT2ACYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |