SCHEMBL8971241

SCHEMBL8971241

CCCCCCCCCCC(OO)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.44
ALDH1A1 P00352 2/20 0.43
NAAA Q02083 2/20 0.43
OPRM1 P35372 3/20 0.43
OPRD1 P41143 3/20 0.43
OPRK1 P41145 3/20 0.43
OPRL1 P41146 3/20 0.43
HTR2A P28223 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SLC7A5 Q01650 1/20 0.41
ASAH1 Q13510 2/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
ACER2 Q5QJU3 1/20 0.40
POLB P06746 1/20 0.40
CNR2 P34972 1/20 0.40
SIGMAR1 Q99720 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28338448 1.00 CSNK1E (0.44) CSNK1EALDH1A1NAAAOPRM1OPRD1
SCHEMBL9617062 0.98 SLC7A5 (0.42) CSNK1EALDH1A1NAAAOPRM1OPRD1
SCHEMBL27487946 0.93 POLB (0.45) ALDH1A1NAAAOPRM1OPRD1OPRK1
SCHEMBL11005389 0.85 HTR2A (0.44) CSNK1EALDH1A1NAAAOPRM1OPRD1
SCHEMBL9168419 0.85 HTR2A (0.44) CSNK1EALDH1A1NAAAOPRM1OPRD1
SCHEMBL7448877 0.85 HTR2A (0.44) CSNK1EALDH1A1NAAAOPRM1OPRD1
SCHEMBL8048483 0.85 HTR2A (0.44) CSNK1EALDH1A1NAAAOPRM1OPRD1
SCHEMBL16057441 0.85 HTR2A (0.44) CSNK1EALDH1A1NAAAOPRM1OPRD1
SCHEMBL3219880 0.85 HTR2A (0.44) CSNK1EALDH1A1NAAAOPRM1OPRD1
SCHEMBL29002040 0.85 HTR2A (0.44) CSNK1EALDH1A1NAAAOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0516885-B1 Styrene/acrylic-type polymers for use as surface sizing agents CYTEC TECH CORP (US) 1996-03-20 EP disclosed
EP-0516885-A1 Styrene/acrylic-type polymers for use as surface sizing agents CYTEC TECHNOLOGY CORP. (US) 1992-12-09 EP disclosed
US-5139614-A Paper sizing comprising a neutralized polymer of styrene or a derivative and methacrylic or acrylic acid; impervious to inks AMERICAN CYANAMID COMPANY (US) 1992-08-18 US disclosed
US-5138004-A For rendering paper to resist penetration of ink or an aqueous liquid KEMIRA OYJ (FI) 1992-08-11 US disclosed
US-5122568-A Solution polymerization in an alcohol/water at reflux temperature using a free-radical catalyst added portion-wise; concurrent neutralization and desolventizing AMERICAN CYANAMID COMPANY (US) 1992-06-16 US disclosed