SCHEMBL8971247

SCHEMBL8971247

CCCCCCCCCc1ccccc1C(C)OO

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 9/20 0.52
CYSLTR1 Q9Y271 9/20 0.52
LIPG Q9Y5X9 1/20 0.51
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
ALOX5 P09917 1/20 0.43
PTGS2 P35354 1/20 0.43
PPARA Q07869 2/20 0.41
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
KAT8 Q9H7Z6 2/20 0.41
PPARG P37231 1/20 0.41
EP300 Q09472 1/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT5 Q92993 1/20 0.41
SAE1 Q9UBE0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482119 0.82 CYSLTR2 (0.47) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL10441855 0.81 CYSLTR2 (0.56) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL500647 0.81 CYSLTR2 (0.56) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL9808865 0.81 CYSLTR2 (0.56) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL27992469 0.81 CYSLTR2 (0.56) CYSLTR2CYSLTR1LIPGTHRATHRB
Hydrogen Peroxide SCHEMBL11209358 0.81 CYSLTR2 (0.60) CYSLTR2CYSLTR1LIPGPPARABID
SCHEMBL10940820 0.81 CYSLTR2 (0.56) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL27299343 0.81 CYSLTR2 (0.56) CYSLTR2CYSLTR1LIPGTHRATHRB
SCHEMBL7059581 0.81 CYSLTR2 (0.55) CYSLTR2CYSLTR1LIPGPPARABID
SCHEMBL17439641 0.81 CYSLTR2 (0.55) CYSLTR2CYSLTR1LIPGPPARABID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0516885-B1 Styrene/acrylic-type polymers for use as surface sizing agents CYTEC TECH CORP (US) 1996-03-20 EP disclosed
EP-0516885-A1 Styrene/acrylic-type polymers for use as surface sizing agents CYTEC TECHNOLOGY CORP. (US) 1992-12-09 EP disclosed
US-5139614-A Paper sizing comprising a neutralized polymer of styrene or a derivative and methacrylic or acrylic acid; impervious to inks AMERICAN CYANAMID COMPANY (US) 1992-08-18 US disclosed
US-5138004-A For rendering paper to resist penetration of ink or an aqueous liquid KEMIRA OYJ (FI) 1992-08-11 US disclosed
US-5122568-A Solution polymerization in an alcohol/water at reflux temperature using a free-radical catalyst added portion-wise; concurrent neutralization and desolventizing AMERICAN CYANAMID COMPANY (US) 1992-06-16 US disclosed