Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 11/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.55 |
| ▸ | KDM5C | P41229 | 1/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.55 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.53 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940895 | 0.98 | KDM5A (0.56) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| SCHEMBL21403268 | 0.98 | KDM5A (0.56) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| SCHEMBL28108337 | 0.98 | KDM5A (0.56) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| SCHEMBL5794324 | 0.98 | KDM5A (0.56) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| SCHEMBL10880115 | 0.90 | KDM4C (0.50) | KDM5AKDM4CPHF8KDM4A | |
| SCHEMBL29238365 | 0.87 | CNR1 (0.60) | — | |
| SCHEMBL28307831 | 0.84 | KDM5A (0.66) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| SCHEMBL3328620 | 0.84 | KDM4C (0.66) | KDM5AKDM4CKDM5CKDM5BPHF8 | |
| SCHEMBL21618528 | 0.82 | — | — | |
| SCHEMBL31749305 | 0.82 | KDM4C (0.69) | KDM5AKDM4CKDM5CKDM5BPHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559677-B1 | HYDROXAMIC ACIDS FOR PREVENTING REPERFUSION INJURY | BRITISH TECH GROUP (GB) | 1996-09-11 | — | — | EP | claimed |
| US-5506266-A | CONTROLS FREE RADICAL INDUCED DAMAGE ARISING FROM MYOCARDIAL INFRACTION OR STROKE, PERTICULARYL HEART DAMAGE | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-04-09 | — | — | US | claimed |
| EP-0559677-A1 | HYDROXAMIC ACIDS FOR PREVENTING REPERFUSION INJURY. | BRITISH TECH GROUP (GB) | 1993-09-15 | — | — | EP | claimed |
| WO-1992008453-A1 | HYDROXAMIC ACIDS FOR PREVENTING REPERFUSION INJURY | BRITISH TECHNOLOGY GROUP LTD (GB) | 1992-05-29 | — | — | WO | claimed |
| US-4874553-A | ADDITIVES FOR IMPROVING PLANT TREATMENT AGENTS | A. NATTERMANN & CIE. GMBH (DE) | 1989-10-17 | — | — | US | disclosed |