SCHEMBL8971436

SCHEMBL8971436

CCCCCOCC(OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.48
HTT P42858 2/20 0.47
LPAR1 Q92633 7/20 0.43
LPAR3 Q9UBY5 7/20 0.43
LPAR2 Q9HBW0 4/20 0.43
SPHK1 Q9NYA1 1/20 0.43
PRKD3 O94806 1/20 0.42
PRKCG P05129 1/20 0.42
PRKCB P05771 1/20 0.42
PRKCA P17252 1/20 0.42
PRKCH P24723 1/20 0.42
PRKCI P41743 1/20 0.42
PRKCE Q02156 1/20 0.42
PRKCQ Q04759 1/20 0.42
PRKCZ Q05513 1/20 0.42
PRKCD Q05655 1/20 0.42
PRKD1 Q15139 1/20 0.42
LPAR5 Q9H1C0 4/20 0.41
LPAR6 P43657 3/20 0.41
LPAR4 Q99677 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10908954 0.98 USP2 (0.52) USP2HTTLPAR1LPAR3LPAR2
SCHEMBL6975117 0.98 USP2 (0.52) USP2HTTLPAR1LPAR3LPAR2
SCHEMBL9850818 0.98 USP2 (0.52) USP2HTTLPAR1LPAR3LPAR2
SCHEMBL28458040 0.94 USP2 (0.48) USP2HTTLPAR1LPAR3LPAR2
SCHEMBL8143953 0.93 TSHR (0.41) USP2HTTLPAR1LPAR3LPAR2
SCHEMBL28357447 0.89 TSHR (0.43) USP2HTTLPAR1LPAR3LPAR2
SCHEMBL703945 0.85 LPAR1 (0.41) USP2HTTLPAR1LPAR3LPAR2
SCHEMBL703310 0.85 LPAR1 (0.41) USP2HTTLPAR1LPAR3LPAR2
SCHEMBL9624071 0.83 HSD17B10 (0.48) USP2HTTTHRB
SCHEMBL11522848 0.83 HTT (0.53) USP2HTTLPAR1LPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493601-B1 LIQUID-CRYSTAL COPOLYMER, PRODUCTION THEREOF, DIENE COMPOUND USED IN SAID PRODUCTION, AND PRODUCTION OF SAID COMPOUND IDEMITSU KOSAN CO (JP) 1996-03-20 EP disclosed
US-5425897-A Electrooptics IDEMITSU KOSAN CO., LTD. (JP) 1995-06-20 US disclosed
US-5380915-A Copolymers of polydimethylsiloxane with diene ethers IDEMITSU KOSAN CO., LTD. (JP) 1995-01-10 US disclosed
US-5281685-A Polyether pendant groups, polysiloxane repeating units IDEMITSU KOSAN CO., LTD. (JP) 1994-01-25 US disclosed
EP-0493601-A1 LIQUID-CRYSTAL COPOLYMER, PRODUCTION THEREOF, DIENE COMPOUND USED IN SAID PRODUCTION, AND PRODUCTION OF SAID COMPOUND IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-07-08 EP disclosed