Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137456 | 0.90 | HMGCR (0.51) | HMGCRKMT2AMAPTPTPN7DGKA | |
| SCHEMBL6137532 | 0.90 | HMGCR (0.48) | HMGCRKMT2AMAPTPTPN7DGKA | |
| SCHEMBL6137305 | 0.90 | HMGCR (0.51) | HMGCRKMT2AMAPTPTPN7DGKA | |
| SCHEMBL6137527 | 0.90 | HMGCR (0.48) | HMGCRKMT2AMAPTPTPN7DGKA | |
| SCHEMBL6137584 | 0.90 | HMGCR (0.51) | HMGCRKMT2AMAPTPTPN7DGKA | |
| SCHEMBL6137577 | 0.90 | HMGCR (0.51) | HMGCRKMT2AMAPTPTPN7DGKA | |
| SCHEMBL6137307 | 0.90 | HMGCR (0.51) | HMGCRKMT2AMAPTPTPN7DGKA | |
| SCHEMBL6138656 | 0.90 | HMGCR (0.48) | HMGCRKMT2AMAPTPTPN7DGKA | |
| SCHEMBL6138650 | 0.90 | HMGCR (0.48) | HMGCRKMT2AMAPTPTPN7DGKA | |
| SCHEMBL6137449 | 0.90 | HMGCR (0.51) | HMGCRKMT2AMAPTPTPN7DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435293-B1 | Methods of producing optically active hydroxyesters | NITTO DENKO CORP (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5272069-A | Method of producing optically active hydroxyesters | NITTO DENKO CO. LTD. (JP) | 1993-12-21 | — | — | US | disclosed |
| EP-0435293-A2 | Methods of producing optically active hydroxyesters | Nitto Denko Co. Ltd. (JP) | 1991-07-03 | — | — | EP | disclosed |