Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.46 |
| ▸ | THRA | P10827 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 5/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 5/20 | 0.38 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878652 | 0.87 | SMN1; SMN2 (0.45) | THRBKMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9877642 | 0.87 | SMN1; SMN2 (0.45) | THRBKMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9879324 | 0.87 | SMN1; SMN2 (0.45) | THRBKMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9877643 | 0.87 | SMN1; SMN2 (0.45) | THRBKMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9879327 | 0.87 | SMN1; SMN2 (0.45) | THRBKMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9878516 | 0.87 | SMN1; SMN2 (0.45) | THRBKMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9878647 | 0.87 | SMN1; SMN2 (0.45) | THRBKMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9878171 | 0.87 | SMN1; SMN2 (0.45) | THRBKMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9878177 | 0.87 | SMN1; SMN2 (0.45) | THRBKMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL9878523 | 0.87 | SMN1; SMN2 (0.45) | THRBKMT2AMAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5560864-A | Liquid crystalline material | MERCK PATENT GESELLSCHAFT MIT BESHRANKTER HAFTUNG (DE) | 1996-10-01 | — | — | US | disclosed |