Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8971764 | 0.86 | NR1H4 (0.49) | NR1H4GAARXRARXRBRXRG | |
| SCHEMBL17911599 | 0.82 | FFAR1 (0.48) | NR1H4RXRARXRBRXRGKMT2A | |
| SCHEMBL39190 | 0.80 | GAA (0.66) | GAARXRARXRBRXRGKMT2A | |
| SCHEMBL5652618 | 0.80 | FFAR1 (0.63) | NR1H4FFAR1ALDH1A1FFAR4 | |
| SCHEMBL28419797 | 0.79 | GAA (0.60) | GAARXRARXRBRXRGKMT2A | |
| SCHEMBL11368092 | 0.79 | GAA (0.64) | GAARXRARXRBRXRGKMT2A | |
| SCHEMBL10554758 | 0.79 | GAA (0.64) | GAARXRARXRBRXRGKMT2A | |
| Methane SCHEMBL2168088 | 0.79 | GAA (0.64) | GAARXRARXRBRXRGKMT2A | |
| Ammonia Solution, Strong SCHEMBL4047307 | 0.79 | GAA (0.64) | GAARXRARXRBRXRGKMT2A | |
| Hydrochloric Acid SCHEMBL7945960 | 0.79 | GAA (0.64) | GAARXRARXRBRXRGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527824-A | ADMINISTERING IN THE TREATMENT OF ASTHMA, PSORIASIS AND ALLERGIC CONDITIONS | RIKER LABORATORIES, INC. (US) | 1996-06-18 | — | — | US | disclosed |
| US-5498745-A | ANTIALLERGEN INTERMEDIATES, INHIBITORS OF LEUKOTRIENES, LIPOXYGENASE INHIBITORS | RIKER LABORATORIES, INC. (US) | 1996-03-12 | — | — | US | disclosed |
| US-5495043-A | ANTIALLERGENS | RIKER LABORATORIES, INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5416113-A | Bronchodilators | RIKER LABORATORIES, INC. (US) | 1995-05-16 | — | — | US | disclosed |
| US-5347036-A | Antiallergens | RIKER LABORATORIES, INC. (US) | 1994-09-13 | — | — | US | disclosed |
| US-5237070-A | Antiallergens, inhibiting bronchoconstriction | RIKER LABORATORIES, INC. (US) | 1993-08-17 | — | — | US | disclosed |
| EP-0212848-B1 | SUBSTITUTED-DI-T-BUTYLPHENOLS | RIKER LABORATORIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0212848-A2 | Substituted-di-t-butylphenols | RIKER LABORATORIES, INC. (US) | 1987-03-04 | — | — | EP | disclosed |