SCHEMBL8972667

SCHEMBL8972667

C[C@@H](NS(=O)(=O)c1ccc2ccccc2c1)C(=O)N(CC1CN(C(=N)N)CCO1)c1cccs1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2 P00734 19/20 0.47
PLG P00747 1/20 0.40
PLAU P00749 1/20 0.40
HPN P05981 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfurous Acid SCHEMBL7292718 0.97 F2 (0.45) F2PLGPLAUHPN
Sulfurous Acid SCHEMBL8579122 0.97 F2 (0.45) F2PLGPLAUHPN
Sulfurous Acid SCHEMBL7300765 0.84 F2 (0.53) F2
SCHEMBL8972680 0.73 F2 (0.45) F2PLGPLAUHPN
SCHEMBL8972657 0.73 F2 (0.45) F2PLGPLAUHPN
Sulfurous Acid SCHEMBL7299947 0.72 F2 (0.55) F2
Sulfurous Acid SCHEMBL7294798 0.70 F2 (0.55) F2
SCHEMBL8717108 0.70 F2 (0.43) F2PLGPLAU
SCHEMBL8972528 0.70 F2 (0.78) F2PLGPLAUHPN
SCHEMBL8972431 0.70 F2 (0.54) F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5583133-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1996-12-10 US claimed