Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312472 | 1.00 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2TAAR1MAOB | |
| SCHEMBL8972763 | 1.00 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2TAAR1MAOB | |
| SCHEMBL8972773 | 1.00 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2TAAR1MAOB | |
| SCHEMBL9312468 | 1.00 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2TAAR1MAOB | |
| SCHEMBL9311971 | 0.89 | SLC6A2 (0.32) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8972361 | 0.89 | SLC6A2 (0.32) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8972367 | 0.89 | SLC6A2 (0.32) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8972357 | 0.89 | SLC6A2 (0.32) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9311977 | 0.89 | SLC6A2 (0.32) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8972754 | 0.85 | MAPK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433836-B1 | Halophenyl substituted dioxanes | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5322638-A | Halophenyl substituted dioxanes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0433836-A2 | Halophenyl substituted dioxanes | F. HOFFMANN-LA ROCHE AG (CH) | 1991-06-26 | — | — | EP | disclosed |