Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973191 | 0.90 | ACACB (0.38) | ACACBABCG2FFAR1MAPTKDM4E | |
| SCHEMBL8972897 | 0.88 | ACACB (0.41) | ACACBABCG2NPC1RAB9AFFAR1 | |
| SCHEMBL8973413 | 0.86 | HAO1 (0.41) | ACACBFFAR1HAO1 | |
| SCHEMBL8972671 | 0.86 | ACACB (0.41) | ACACBFFAR1MAPTSMN1; SMN2HAO1 | |
| SCHEMBL8961084 | 0.85 | FFAR1 (0.48) | ACACBABCG2FFAR1KDM4E | |
| SCHEMBL8972830 | 0.85 | FFAR1 (0.43) | ACACBABCG2FFAR1KDM4E | |
| SCHEMBL8973059 | 0.84 | PTGDR2 (0.39) | ACACBFFAR1MAPTHAO1 | |
| SCHEMBL8961234 | 0.84 | ACACB (0.37) | ACACBABCG2NPC1RAB9AFFAR1 | |
| SCHEMBL8972898 | 0.82 | FFAR1 (0.38) | ACACBABCG2NPC1FFAR1KDM4E | |
| SCHEMBL9128248 | 0.82 | NPC1 (0.43) | ACACBNPC1RAB9AFFAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566455-B1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-03-06 | — | — | EP | disclosed |
| US-5451696-A | Parasiticide intermediate | ROUSSEL-UCLAF (FR) | 1995-09-19 | — | — | US | disclosed |
| US-5380883-A | Insecticide, nematocide, miticide | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| EP-0566455-A1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-10-20 | — | — | EP | disclosed |