SCHEMBL8973448

SCHEMBL8973448

Cc1cc(N=C=O)ccc1-c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.51
TRPA1 O75762 1/20 0.51
ESR2 Q92731 1/20 0.49
TDP1 Q9NUW8 2/20 0.42
MAPK1 P28482 1/20 0.42
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37
TSHR P16473 1/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
GAA P10253 2/20 0.36
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
EPHX1 P07099 1/20 0.35
CYP2A6 P11509 1/20 0.35
CYP2B6 P20813 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29808709 0.91 CYP3A4 (0.56) CYP3A4TRPA1ESR2TDP1MAPK1
SCHEMBL8596339 0.91 CYP3A4 (0.56) CYP3A4TRPA1ESR2TDP1MAPK1
SCHEMBL543864 0.89 CYP3A4 (0.55) CYP3A4TRPA1ESR2TDP1MAPK1
SCHEMBL8596343 0.86 CYP3A4 (0.55) CYP3A4TRPA1ESR2TDP1MAPK1
SCHEMBL667517 0.85 CYP3A4 (0.62) CYP3A4TRPA1ESR2TDP1MAPK1
SCHEMBL7061343 0.84 MAPK1 (0.46) CYP3A4TRPA1ESR2TDP1MAPK1
SCHEMBL8589469 0.83 CYP3A4 (0.49) CYP3A4TRPA1TDP1MAPK1PDE3B
SCHEMBL9229680 0.81 MAPK1 (0.43) CYP3A4TRPA1TDP1MAPK1TSHR
SCHEMBL5171045 0.81 CYP3A4 (0.53) CYP3A4TRPA1ESR2TDP1MAPK1
SCHEMBL14688874 0.81 MAPK1 (0.43) CYP3A4TRPA1TDP1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116997590-A Polyol and process for producing the same 巴斯夫欧洲公司 2023-11-03 CN claimed
CN-116964122-A Polyurea copolymers 巴斯夫欧洲公司 2023-10-27 CN claimed
CN-114846043-A Polyurea copolymers 巴斯夫欧洲公司 2022-08-02 CN claimed
CN-114829442-A Polyurea copolymers 巴斯夫欧洲公司 2022-07-29 CN claimed
CN-116997590-A Polyol and process for producing the same 巴斯夫欧洲公司 2023-11-03 CN disclosed
CN-116964122-A Polyurea copolymers 巴斯夫欧洲公司 2023-10-27 CN disclosed
CN-114846043-A Polyurea copolymers 巴斯夫欧洲公司 2022-08-02 CN disclosed
CN-114829442-A Polyurea copolymers 巴斯夫欧洲公司 2022-07-29 CN disclosed
EP-0702709-A1 ANHYDRIDE-EPOXY COATING COMPOSITION MODIFIED WITH A FLUOROPOLYMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-03-27 EP disclosed
WO-1994026830-A1 ANHYDRIDE-EPOXY COATING COMPOSITION MODIFIED WITH A FLUOROPOLYMER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-11-24 WO disclosed