SCHEMBL8973646

SCHEMBL8973646

CCCCN(C)CC=Cc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NR1I2 O75469 1/20 0.50
DRD2 P14416 1/20 0.50
ADRA2C P18825 1/20 0.50
CNR1 P21554 1/20 0.50
SLC6A2 P23975 1/20 0.50
HTR2A P28223 1/20 0.50
SLC6A4 P31645 1/20 0.50
ADRA1A P35348 1/20 0.50
OPRK1 P41145 1/20 0.50
SLC6A3 Q01959 1/20 0.50
EBP Q15125 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
TSHR P16473 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12507269 1.00 KCNH2 (0.50) KCNH2MEN1KMT2ANR1I2DRD2
SCHEMBL12507449 0.85 MEN1 (0.49) KCNH2MEN1KMT2ANR1I2DRD2
SCHEMBL3305915 0.84 KCNH2 (0.62) KCNH2MEN1KMT2ANR1I2DRD2
SCHEMBL3305918 0.84 KCNH2 (0.62) KCNH2MEN1KMT2ANR1I2DRD2
SCHEMBL12507453 0.83 MEN1 (0.48) KCNH2MEN1KMT2ANR1I2DRD2
SCHEMBL5426275 0.83 HTR2A (0.60) KCNH2MEN1KMT2ANR1I2DRD2
SCHEMBL5426277 0.83 HTR2A (0.60) KCNH2MEN1KMT2ANR1I2DRD2
SCHEMBL12507450 0.82 MEN1 (0.65) KCNH2MEN1KMT2ANR1I2DRD2
SCHEMBL8919687 0.81 MEN1 (0.51) KCNH2MEN1KMT2ANR1I2DRD2
SCHEMBL6976076 0.81 MEN1 (0.51) KCNH2MEN1KMT2ANR1I2DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0439072-B1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1996-04-03 EP disclosed
EP-0389928-B1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1995-08-02 EP disclosed
EP-0432727-B1 Electrophotographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1995-07-05 EP disclosed
EP-0307227-B1 Electrophotographic photoreceptor FUJI PHOTO FILM CO LTD (JP) 1995-06-28 EP disclosed
US-5227272-A Layer containing inorganic photoconductor and binder resin with block copolymer composed of acidic component and hydrocarbyl methacrylate component FUJI PHOTO FILM CO., LTD. (JP) 1993-07-13 US disclosed
US-5183721-A Photoconductive particles and binder resin FUJI PHOTO FILM CO., LTD. (JP) 1993-02-02 US disclosed
US-5147752-A Crosslinked binder FUJI PHOTO FILM CO., LTD. (JP) 1992-09-15 US disclosed
US-5089368-A Binder resin of graft copolymer made from an acid group-containing macromolecular block polymer monomer FUJI PHOTO FILM CO., LTD. (JP) 1992-02-18 US disclosed
US-5063130-A Photoconductive layer containing inorganic particles and a binder comprising an acrylic copolymer having a polyester macromonomer; electrostatics; moisture resistance; durability FUJI PHOTO FILM CO., LTD. (JP) 1991-11-05 US disclosed
EP-0439072-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-31 EP disclosed
EP-0432727-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-06-19 EP disclosed
US-4968572-A EXCELLENT ELECTROSTATIC CHARACTERISTICS AND IMAGE FORMATION PERFORMANCE IN SPITE OF HEAT AND HUMIDITY FUJI PHOTO FILM CO., LTD. (JP) 1990-11-06 US disclosed
EP-0389928-A2 Electrophotographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-10-03 EP disclosed