Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | APAF1 | O14727 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.55 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973793 | 1.00 | TDP1 (0.60) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Hydrochloric Acid SCHEMBL11006527 | 0.99 | TDP1 (0.59) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL11569737 | 0.89 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL11569732 | 0.89 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5327994 | 0.89 | TDP1 (0.77) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5487622 | 0.89 | TDP1 (0.77) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5487631 | 0.89 | TDP1 (0.77) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5328002 | 0.89 | TDP1 (0.77) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL11468182 | 0.88 | TDP1 (0.60) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL11568371 | 0.88 | TDP1 (0.60) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440766-A | CEPHALOSPORINS; BACTERICIDES; MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-04-03 | — | — | US | claimed |
| US-5585485-A | Cephalosporin intermediate products | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1996-12-17 | — | — | US | disclosed |
| US-5484928-A | 2-(2-aminothiazol-4-yl)-2-oxoacetic acid derivatives | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1996-01-16 | — | — | US | disclosed |
| US-4201779-A | 7[(2-Amino-thiazol-4-yl)glyoxylamido]-cephem derivatives and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-06 | — | — | US | disclosed |