Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975499 | 0.83 | FFAR1 (0.49) | FFAR1PPARGPPARA | |
| SCHEMBL8975496 | 0.82 | MAPK1 (0.58) | FFAR1PPARGHRH3PPARA | |
| SCHEMBL8975066 | 0.78 | FFAR1 (0.51) | FFAR1PPARGPPARA | |
| SCHEMBL8975030 | 0.78 | FFAR1 (0.52) | FFAR1PPARGHRH3PPARA | |
| SCHEMBL8304663 | 0.77 | HRH3 (0.56) | FFAR1PPARGHRH3PPARA | |
| SCHEMBL1299621 | 0.75 | FFAR1 (0.83) | FFAR1PPARGPPARA | |
| SCHEMBL8974565 | 0.73 | FFAR1 (0.49) | FFAR1PPARGHRH3PPARA | |
| SCHEMBL1072226 | 0.73 | FFAR1 (0.77) | FFAR1PPARGHRH3PPARA | |
| SCHEMBL8974634 | 0.73 | FFAR1 (0.49) | FFAR1PPARGHRH3PPARA | |
| SCHEMBL9242566 | 0.73 | PPARG (0.52) | FFAR1PPARGHRH3PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578620-A | TREATMENT OF DIABETES AND HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0678511-A2 | Thiazolidine and oxazolidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1995-10-25 | — | — | EP | disclosed |