Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.49 |
| ▸ | MPC2 | O95563 | 1/20 | 0.46 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8975392 | 1.00 | PPARG (0.49) | PPARGMPC2CYP2C8CYP2C9GRM2 | |
| SCHEMBL8974643 | 1.00 | PPARG (0.49) | PPARGMPC2CYP2C8CYP2C9GRM2 | |
| SCHEMBL8975354 | 1.00 | PPARG (0.49) | PPARGMPC2CYP2C8CYP2C9GRM2 | |
| SCHEMBL8974648 | 1.00 | PPARG (0.49) | PPARGMPC2CYP2C8CYP2C9GRM2 | |
| SCHEMBL8975359 | 1.00 | PPARG (0.49) | PPARGMPC2CYP2C8CYP2C9GRM2 | |
| SCHEMBL8975396 | 1.00 | PPARG (0.49) | PPARGMPC2CYP2C8CYP2C9GRM2 | |
| SCHEMBL8974627 | 0.92 | PPARG (0.47) | PPARGMPC2CYP2C8CYP2C9GRM2 | |
| SCHEMBL8975081 | 0.92 | PPARG (0.47) | PPARGMPC2CYP2C8CYP2C9GRM2 | |
| SCHEMBL8974634 | 0.91 | FFAR1 (0.49) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL8974613 | 0.91 | PPARG (0.47) | PPARGMPC2CYP2C8CYP2C9GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578620-A | TREATMENT OF DIABETES AND HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1996-11-26 | — | — | US | claimed |
| US-5578620-A | TREATMENT OF DIABETES AND HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0678511-A2 | Thiazolidine and oxazolidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1995-10-25 | — | — | EP | disclosed |