Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | F11 | P03951 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | HMGCR | P04035 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13169183 | 1.00 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL8587293 | 1.00 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL12352428 | 1.00 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL15481989 | 1.00 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL10700635 | 1.00 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL14349362 | 1.00 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL11232105 | 1.00 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL22983992 | 1.00 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL22984008 | 1.00 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A | |
| SCHEMBL7151003 | 1.00 | PTPN1 (0.57) | PTPN1USP2MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506347-A | ADENOSINE KINASE INHIBITOR | GENSIA, INC. (US) | 1996-04-09 | — | — | US | disclosed |