Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 5/20 | 0.38 |
| ▸ | NPY1R | P25929 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | OTC | P00480 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604856 | 1.00 | MEN1 (0.45) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL604855 | 1.00 | MEN1 (0.45) | MEN1GAAKMT2AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL27482850 | 0.98 | MEN1 (0.44) | MEN1GAAKMT2AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL8376792 | 0.98 | MEN1 (0.44) | MEN1GAAKMT2AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL29398231 | 0.98 | MEN1 (0.44) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL5847744 | 0.89 | MEN1 (0.41) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL20468063 | 0.88 | MEN1 (0.37) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL14414714 | 0.88 | MEN1 (0.45) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL14090836 | 0.88 | MEN1 (0.45) | MEN1GAAKMT2AMAOAMAOB | |
| SCHEMBL30860176 | 0.88 | MEN1 (0.47) | MEN1GAAKMT2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350221-B1 | Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same | ASTRA AB (SE) | 1996-04-17 | — | — | EP | disclosed |
| US-5312899-A | Dermorphin analogs | BIOCHEM PHARMA, INC. (CA) | 1994-05-17 | — | — | US | disclosed |
| EP-0350221-A2 | Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same | Astra Aktiebolag (SE) | 1990-01-10 | — | — | EP | disclosed |