Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 12/20 | 0.47 |
| ▸ | EDNRA | P25101 | 12/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872070 | 0.87 | EDNRB (0.48) | EDNRBEDNRACYP1A2KDM4EALDH1A1 | |
| Lithium Ion SCHEMBL8871070 | 0.84 | EDNRB (0.46) | EDNRBEDNRACYP1A2MAPTKMT2A | |
| SCHEMBL8871426 | 0.82 | EDNRB (0.42) | EDNRBEDNRACYP1A2KDM4EALDH1A1 | |
| SCHEMBL8871463 | 0.81 | EDNRB (0.51) | EDNRBEDNRAKCNN4CYP1A2KDM4E | |
| SCHEMBL8873369 | 0.80 | EDNRB (0.49) | EDNRBEDNRAKCNN4CYP1A2KDM4E | |
| SCHEMBL8975735 | 0.80 | EDNRB (0.47) | EDNRBEDNRAKCNN4CYP1A2KDM4E | |
| SCHEMBL2419456 | 0.79 | KCNN4 (0.64) | KCNN4CYP1A2ALDH1A1MAPTKMT2A | |
| SCHEMBL8872002 | 0.77 | EDNRB (0.44) | EDNRBEDNRAKCNN4CYP1A2KDM4E | |
| SCHEMBL8975656 | 0.74 | EDNRB (0.49) | EDNRBEDNRAKDM4EALDH1A1MAPT | |
| SCHEMBL12095209 | 0.73 | EDNRB (0.52) | EDNRBEDNRAKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502028-A | Herbicidal pyrimidinyl or triazinyl haloacetic acid derivatives | SCHERING AGROCHEMICALS LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |
| EP-0575404-A1 | HERBICIDES | AgrEvo UK Limited (GB) | 1993-12-29 | — | — | EP | disclosed |
| WO-1992016511-A1 | HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |