Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 14/20 | 0.72 |
| ▸ | AKR1C2 | P52895 | 14/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17082611 | 0.94 | AKR1C3 (0.65) | AKR1C3AKR1C2MAPTKDM4ENPC1 | |
| SCHEMBL9593414 | 0.91 | AKR1C3 (0.74) | AKR1C3AKR1C2MAPTKDM4ENPC1 | |
| SCHEMBL936023 | 0.87 | AKR1C3 (0.69) | AKR1C3AKR1C2MAPTKDM4ENPC1 | |
| SCHEMBL17082614 | 0.86 | AKR1C3 (0.56) | AKR1C3AKR1C2MAPTKDM4ENPC1 | |
| SCHEMBL9593591 | 0.86 | AKR1C3 (0.79) | AKR1C3AKR1C2MAPTGFERSMN1; SMN2 | |
| SCHEMBL6601352 | 0.86 | AKR1C3 (0.66) | AKR1C3AKR1C2MAPTKDM4EGAA | |
| SCHEMBL11417902 | 0.85 | AKR1C3 (0.67) | AKR1C3AKR1C2MAPTKDM4ENPC1 | |
| SCHEMBL17190218 | 0.84 | AKR1C3 (0.54) | AKR1C3AKR1C2MAPTKDM4ENPC1 | |
| SCHEMBL9409077 | 0.84 | AKR1C3 (0.64) | AKR1C3AKR1C2MAPTKDM4ENPC1 | |
| SCHEMBL26865928 | 0.83 | AKR1C3 (0.64) | AKR1C3AKR1C2MAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558511-B1 | METHOD OF PREPARING 2,5-DI(PHENYLAMINO)TEREPHTHALIC ACID AND ITS DIALKYL ESTERS AS HIGH-PURITY PRODUCTS | HOECHST AG (DE) | 1996-04-17 | — | — | EP | disclosed |
| US-5347038-A | Starting material for quinacridone pigments, pollution control, from succinic acid diester and aniline | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-09-13 | — | — | US | disclosed |
| EP-0558511-A1 | METHOD OF PREPARING 2,5-DI(PHENYLAMINO)TEREPHTHALIC ACID AND ITS DIALKYL ESTERS AS HIGH-PURITY PRODUCTS. | HOECHST AG (DE) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009558-A1 | METHOD OF PREPARING 2,5-DI(PHENYLAMINO)TEREPHTHALIC ACID AND ITS DIALKYL ESTERS AS HIGH-PURITY PRODUCTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-11 | — | — | WO | disclosed |