Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.74 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CCNH | P51946 | 1/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL15569981 | 0.87 | TP53 (0.70) | TP53FLT1FLT4KDRTSHR | |
| SCHEMBL29349499 | 0.86 | — | — | |
| SCHEMBL22730 | 0.86 | — | — | |
| SCHEMBL8873179 | 0.86 | TP53 (1.00) | TP53TSHRTDP1ALDH1A1CYP3A4 | |
| Sulfuric Acid SCHEMBL1303187 | 0.85 | TP53 (0.67) | TP53FLT1FLT4KDRTSHR | |
| Sulfuric Acid SCHEMBL19739057 | 0.85 | TP53 (0.67) | TP53FLT1FLT4KDRTSHR | |
| Sulfuric Acid SCHEMBL29653821 | 0.85 | TP53 (0.67) | TP53FLT1FLT4KDRTSHR | |
| Sulfuric Acid SCHEMBL29653807 | 0.85 | TP53 (0.67) | TP53FLT1FLT4KDRTSHR | |
| Sulfuric Acid SCHEMBL1303189 | 0.85 | TP53 (0.67) | TP53FLT1FLT4KDRTSHR | |
| Sulfuric Acid SCHEMBL17801639 | 0.85 | TP53 (0.67) | TP53FLT1FLT4KDRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011168-B | Synthesis intermediates of cytosines and synthesis intermediates of thionucleosides | 富士胶片株式会社 | 2020-06-09 | — | — | CN | disclosed |
| CN-103012407-B | N-[4-(1H-pyrazolo [3,4-b] pyrazine-6-base)-phenyl]-sulfonamides and the purposes as medicine thereof | 赛诺菲 | 2016-06-29 | — | — | CN | disclosed |
| CN-104540803-A | Synthesis intermediate of 1- (2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl) cytosine, synthesis intermediate of thionucleoside, and processes for producing these | FUJIFILM CORP | 2015-04-22 | — | — | CN | disclosed |
| CN-103596925-A | Benzocycloheptene acetic acids | HOFFMANN LA ROCHE | 2014-02-19 | — | — | CN | disclosed |
| CN-1964965-B | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE | 2012-07-04 | — | — | CN | disclosed |
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |
| CN-101511783-A | N-biaryl (hetero) arylsulphonamide derivatives useful in the treatment of diseases mediated by lymphocytes interactions | NOVARTIS AG (CH) | 2009-08-19 | — | — | CN | disclosed |
| CN-1964965-A | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives | CEPHALON FRANCE (FR) | 2007-05-16 | — | — | CN | disclosed |
| CN-1249039-C | Inhibitors of 11 beta-hydroxysteroid dehydrogenase type I | BIOVITRUM AB (SE) | 2006-04-05 | — | — | CN | disclosed |
| CN-1150205-C | 3-mercaptoacetylamino-1,5-subsd. 2-oxo-azepon derivatives useful as inhibitor of metrix metalloproteinase | ���µ�˹ҩ�﹫˾ | 2004-05-19 | — | — | CN | disclosed |
| CN-1054975-A | Produce the method for new 5-fluorine nicotinic acid or derivatives thereof or its carboxyl response activity derivant and their salt | TOYAMA CHEMICAL CO LTD (JP) | 1991-10-02 | — | — | CN | disclosed |
| CN-86100879-A | Novel process for preparing 1-substituted aryl-1, 4-dihydro-4-oxo-1, 8-naphthyridine derivatives and intermediates thereof | — | 1986-12-17 | — | — | CN | disclosed |
| US-4163005-A | FOR USE IN POLYMER COMPOSITIONS | VELSICOL CHEMICAL CORPORATION (US) | 1979-07-31 | — | — | US | disclosed |
| US-4093445-A | FOR THIOCARBAMATE HERBICIDES | STAUFFER CHEMICAL (US) | 1978-06-06 | — | — | US | disclosed |
| US-4071351-A | Sulfonamide herbicide antidote compositions and methods of use | STAUFFER CHEMICAL COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-4071350-A | THIOCARBAMATES | STAUFFER CHEMICAL COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-4071352-A | Sulfonamide herbicide antidote compositions and methods of use | STAUFFER CHEMICAL COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-4071349-A | Sulfonamide herbicide antidote compositions and methods of use | STAUFFER CHEMICAL COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-4071353-A | Sulfonamide herbicide antidote compositions and methods of use | STAUFFER CHEMICAL COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
| US-4021229-A | THIOCARBAMATE | STAUFFER CHEMICAL COMPANY (US) | 1977-05-03 | — | — | US | disclosed |