Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976298 | 1.00 | GABRR1 (0.35) | GABRR1GABBR2GABBR1 | |
| SCHEMBL8751367 | 1.00 | GABRR1 (0.35) | GABRR1GABBR2GABBR1 | |
| SCHEMBL8976497 | 0.87 | — | — | |
| SCHEMBL8751336 | 0.87 | — | — | |
| SCHEMBL8751271 | 0.84 | — | — | |
| SCHEMBL8976334 | 0.77 | GABRR1 (0.41) | GABRR1GABBR2GABBR1 | |
| SCHEMBL8751329 | 0.77 | GABRR1 (0.41) | GABRR1GABBR2GABBR1 | |
| SCHEMBL8751327 | 0.77 | GABRR1 (0.41) | GABRR1GABBR2GABBR1 | |
| SCHEMBL777100 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL8751280 | 0.70 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500418-A | ANTIEPILEPTIC | CIBA-GEIGY CORPORATION (US) | 1996-03-19 | — | — | US | disclosed |
| US-5376684-A | Aminobutyric acid antagonist; antiepileptic agent | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |