SCHEMBL8976825

SCHEMBL8976825

FC(F)(F)C1(C(F)(F)F)OC(F)(Br)C(F)(Br)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375225 0.73
SCHEMBL10966627 0.71
SCHEMBL3108368 0.69
SCHEMBL8616401 0.69
SCHEMBL8891328 0.69
SCHEMBL3412310 0.69
SCHEMBL6017537 0.67
SCHEMBL8977092 0.65
SCHEMBL16372512 0.65
SCHEMBL8998663 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499157-B1 Process for preparing 1,3-dioxoles AUSIMONT SPA (IT) 1996-04-24 EP disclosed
EP-0499158-B1 Process for the dehalogenation of 1,3-dioxolanes AUSIMONT SPA (IT) 1995-06-28 EP disclosed
EP-0491872-B1 POLYHALODIHYDRODIOXINS AND POLYHALODIOXOLES DU PONT (US) 1994-08-03 EP disclosed
US-5296617-A Process for preparing 1,3-dioxoles AUSIMONT S.P.A. (IT) 1994-03-22 US disclosed
US-5286825-A Copolymer of tetrafluoroethylene and bis-2,2-trifluoromethyl-4,5-difluorodivinyl-1,3-dioxolanes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-02-15 US disclosed
US-5245054-A PROCESS FOR THE DEHALOGENATION OF 1,3-DIOXOLANES SPHERILENE S.R.L. (IT) 1993-09-14 US disclosed
US-5233058-A Fluoro-2,2-dimethyldioxolanes; copolymers with tetrafluoroethylene E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-08-03 US disclosed
EP-0504322-A1 PARTIALLY FLUORINATED COMPOUNDS AND POLYMERS. DU PONT (US) 1992-09-23 EP disclosed
EP-0499158-A1 Process for the dehalogenation of 1,3-dioxolanes AUSIMONT S.p.A. (IT) 1992-08-19 EP disclosed
EP-0499157-A1 Process for preparing 1,3-dioxoles AUSIMONT S.p.A. (IT) 1992-08-19 EP disclosed
WO-1991009025-A2 PARTIALLY FLUORINATED COMPOUNDS AND POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-06-27 WO disclosed
US-3978030-A Polymers of fluorinated dioxoles E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-08-31 US disclosed