Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2835919 | 0.90 | USP2 (0.50) | USP2HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL2420872 | 0.90 | USP2 (0.50) | USP2HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL11042865 | 0.90 | USP2 (0.50) | USP2HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL17629258 | 0.90 | USP2 (0.50) | USP2HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL2839409 | 0.90 | USP2 (0.50) | USP2HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL11572401 | 0.90 | USP2 (0.50) | USP2HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL28854829 | 0.82 | PLA2G2C (0.43) | USP2HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL10438663 | 0.82 | PRKD3 (0.51) | USP2HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL8086425 | 0.82 | PRKD3 (0.51) | USP2HTTLPAR1LPAR3LPAR2 | |
| SCHEMBL8081125 | 0.82 | PRKD3 (0.51) | USP2HTTLPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512671-A | VIRICIDES | WAKE FOREST UNIVERSITY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0533825-B1 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES | UNIV WAKE FOREST (US) | 1996-04-24 | — | — | EP | disclosed |
| EP-0533825-A4 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES | — | 1993-06-02 | — | — | EP | disclosed |
| EP-0533825-A1 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES. | UNIV WAKE FOREST (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991019726-A1 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES | WAKE FOREST UNIVERSITY (US) | 1991-12-26 | — | — | WO | disclosed |