Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HK1 | P19367 | 1/20 | 0.47 |
| ▸ | HK2 | P52789 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MANBA | O00462 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Galactose SCHEMBL8955287 | 0.83 | ERN1 (0.62) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| D-Galactose SCHEMBL8956183 | 0.82 | CYP1A2 (0.51) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| Dextrose SCHEMBL769631 | 0.81 | HK1 (0.50) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| B-D-Galactose SCHEMBL10543506 | 0.81 | HK1 (0.50) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| D-Mannose SCHEMBL28638354 | 0.81 | HK1 (0.50) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| D-Galactose SCHEMBL769918 | 0.81 | HK1 (0.50) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| B-D-Galactose SCHEMBL7519216 | 0.81 | HK1 (0.50) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| Beta-D-Glucose SCHEMBL344866 | 0.81 | HK1 (0.50) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| B-D-Galactose SCHEMBL8600245 | 0.81 | HK1 (0.50) | CYP1A2NFKB1THPOALDH1A1PMP22 | |
| B-D-Galactose SCHEMBL27713886 | 0.81 | HK1 (0.50) | CYP1A2NFKB1THPOALDH1A1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421589-B1 | Drug screening assay | MICROGENICS CORP (US) | 1996-04-03 | — | — | EP | disclosed |
| US-5434052-A | Complementation assay for drug screening | MICROGENICS CORPORATION (US) | 1995-07-18 | — | — | US | disclosed |
| EP-0421589-A2 | Drug screening assay | MICROGENICS CORPORATION (US) | 1991-04-10 | — | — | EP | disclosed |