Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700418 | 0.95 | TDP1 (0.62) | TDP1CYP19A1CYSLTR2CYSLTR1MAPT | |
| SCHEMBL11232774 | 0.92 | TDP1 (0.65) | TDP1CYP19A1MAPTALDH1A1LMNA | |
| SCHEMBL29469600 | 0.91 | TDP1 (0.64) | TDP1CYP19A1MAPTALDH1A1LMNA | |
| SCHEMBL397794 | 0.91 | TDP1 (0.64) | TDP1CYP19A1MAPTALDH1A1LMNA | |
| SCHEMBL4800134 | 0.90 | CYP19A1 (0.61) | TDP1CYP19A1CYSLTR2CYSLTR1MAPT | |
| SCHEMBL11224639 | 0.89 | TDP1 (0.65) | TDP1MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL11419463 | 0.89 | TDP1 (0.55) | TDP1CYP19A1CYSLTR2CYSLTR1MAPT | |
| SCHEMBL11426633 | 0.89 | TDP1 (0.55) | TDP1CYP19A1CYSLTR2CYSLTR1MAPT | |
| SCHEMBL11421627 | 0.88 | TDP1 (0.65) | TDP1CYP19A1MAPTALDH1A1LMNA | |
| SCHEMBL3296474 | 0.88 | CYP19A1 (0.63) | TDP1CYP19A1CYSLTR2CYSLTR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517871-B1 | NOVEL NITROANILIDES AND THEIR PREPARATION | KODAK LTD (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5382682-A | Nitroanilides and their preparation | EASTMAN KODAK COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0517871-A1 | NOVEL NITROANILIDES AND THEIR PREPARATION. | KODAK LTD (GB) | 1992-12-16 | — | — | EP | disclosed |
| WO-1992011230-A1 | NOVEL NITROANILIDES AND THEIR PREPARATION | KODAK LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |