Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | P4HB | P07237 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12450812 | 0.84 | PTPN1 (0.56) | TSHRCYP2D6THRBHSD17B10CA2 | |
| SCHEMBL13875363 | 0.84 | TSHR (0.49) | TSHRLMNACYP2D6THRBHSD17B10 | |
| SCHEMBL2342815 | 0.84 | CYP2D6 (0.49) | TSHRLMNACYP2D6THRBHSD17B10 | |
| SCHEMBL13875372 | 0.84 | CYP2D6 (0.49) | TSHRLMNACYP2D6THRBHSD17B10 | |
| SCHEMBL23742930 | 0.83 | TSHR (0.64) | TSHRLMNACYP2D6THRBHSD17B10 | |
| SCHEMBL13617226 | 0.83 | TSHR (0.64) | TSHRLMNACYP2D6THRBHSD17B10 | |
| SCHEMBL15514610 | 0.83 | TSHR (0.64) | TSHRLMNACYP2D6THRBHSD17B10 | |
| SCHEMBL8722654 | 0.83 | TSHR (0.64) | TSHRLMNACYP2D6THRBHSD17B10 | |
| SCHEMBL10359936 | 0.83 | TSHR (0.64) | TSHRLMNACYP2D6THRBHSD17B10 | |
| SCHEMBL8722653 | 0.83 | TSHR (0.64) | TSHRLMNACYP2D6THRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5481043-A | ANTIINFLAMMATORY AGENTS FOR ALLERGIC LUNG DISEASES | PLANTAMED ARZNEIMITTEL GMBH (DE) | 1996-01-02 | — | — | US | disclosed |