Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688156 | 0.82 | MAPT (0.46) | LMNAMAPTRECQLMEN1ALDH1A1 | |
| SCHEMBL12926197 | 0.80 | KDM4E (0.54) | LMNAMAPTRECQLALDH1A1KDM4E | |
| SCHEMBL9689826 | 0.80 | MAPT (0.46) | LMNAMAPTRECQLMEN1ALDH1A1 | |
| SCHEMBL9688758 | 0.80 | MAPT (0.46) | LMNAMAPTRECQLMEN1ALDH1A1 | |
| SCHEMBL28719784 | 0.79 | KDM4E (0.47) | LMNAMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL28854277 | 0.77 | RECQL (0.56) | LMNAMAPTRECQLMEN1ALDH1A1 | |
| SCHEMBL11731940 | 0.77 | RECQL (0.61) | LMNAMAPTRECQLMEN1ALDH1A1 | |
| SCHEMBL25390546 | 0.75 | MAPT (0.54) | LMNAMAPTALDH1A1KDM4EPOLB | |
| SCHEMBL5252962 | 0.75 | CNR2 (0.55) | LMNAMAPTKDM4ECNR2RAB9A | |
| SCHEMBL1607395 | 0.74 | CNR2 (0.57) | LMNAMAPTALDH1A1KDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512537-A | 2-benzoyl pyrrole and benzoyl imidazole herbicides | ZENECA LIMITED (GB) | 1996-04-30 | — | — | US | disclosed |