Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22620711 | 0.89 | KDM4E (0.56) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28667622 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL22620710 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL22953013 | 0.85 | KDM4E (0.52) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL27782466 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL701020 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7680542 | 0.82 | SRD5A2 (0.49) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL28687264 | 0.81 | HRH3 (0.54) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL913891 | 0.81 | KDM4E (0.56) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4044123 | 0.80 | CDK1 (0.57) | KDM4EALDH1A1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708091-A2 | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |