Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.45 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037117 | 0.90 | MRGPRX4 (0.52) | CYSLTR2CYSLTR1LTB4RLTB4R2MRGPRX4 | |
| SCHEMBL8777268 | 0.87 | MRGPRX4 (0.40) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL8977804 | 0.86 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1LTB4RLTB4R2 | |
| SCHEMBL8977815 | 0.82 | CYSLTR1 (0.45) | CYSLTR2CYSLTR1LTB4RLTB4R2PPARG | |
| SCHEMBL2894665 | 0.80 | MRGPRX4 (0.53) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL8977832 | 0.79 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1LTB4RLTB4R2PPARG | |
| SCHEMBL8825187 | 0.78 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1LTB4RLTB4R2PPARG | |
| SCHEMBL8777242 | 0.77 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1LTB4RLTB4R2PPARG | |
| SCHEMBL8777258 | 0.77 | MRGPRX4 (0.53) | MRGPRX4PDE5A | |
| SCHEMBL8777254 | 0.76 | MRGPRX4 (0.40) | CYSLTR2CYSLTR1LTB4RLTB4R2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559134-A | Leukotriene-B4 antagonists, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | claimed |
| US-5559134-A | Leukotriene-B4 antagonists, process for their production and their use as pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-09-24 | — | — | US | disclosed |