Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236459 | 0.73 | TDP1 (0.33) | — | |
| SCHEMBL10595796 | 0.73 | — | — | |
| SCHEMBL29712073 | 0.73 | TDP1 (0.33) | — | |
| SCHEMBL3231602 | 0.73 | — | — | |
| SCHEMBL23092892 | 0.70 | KDM4E (0.38) | CHEK1 | |
| SCHEMBL31561553 | 0.70 | CHEK1 (0.41) | CHEK1 | |
| SCHEMBL45555 | 0.67 | KDM4E (0.35) | — | |
| SCHEMBL23291651 | 0.63 | CA12 (0.42) | — | |
| SCHEMBL13734808 | 0.62 | KDM4E (0.50) | — | |
| SCHEMBL23291650 | 0.61 | SMARCA2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709722-A1 | Silver halide photographic element and method for stabilizing a light-sensitive silver halide emulsion | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0441339-A1 | Substituted triazolopyridazines | MERRELL PHARMACEUTICALS INC. (US) | 1991-08-14 | — | — | EP | disclosed |
| US-5011835-A | Substituted triazolopyridazines, pharmaceutical compositions and use | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-30 | — | — | US | disclosed |