Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ICMT | O60725 | 9/20 | 0.52 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
| ▸ | FNTB | P49356 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977916 | 1.00 | MAPT (0.57) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL2880044 | 1.00 | MAPT (0.57) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL2880046 | 1.00 | MAPT (0.57) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL4352903 | 1.00 | MAPT (0.57) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL14663234 | 1.00 | MAPT (0.57) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL14596316 | 1.00 | MAPT (0.57) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL1741964 | 0.88 | MAPT (0.53) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL3402724 | 0.88 | MAPT (0.53) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL15527709 | 0.86 | MAPT (0.51) | MAPTALDH1A1MEN1TRPA1KMT2A | |
| SCHEMBL2821557 | 0.85 | MAPT (0.65) | MAPTALDH1A1MEN1TRPA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571687-A | TREATING CELLS WITH SPECIFIED COMPOUNDS TO EFFECT EXPRESSION OF MEMBRANE TRANSPORTER | DUKE UNIVERSITY (US) | 1996-11-05 | — | — | US | disclosed |