Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.60 |
| ▸ | CNR2 | P34972 | 7/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 9/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4651843 | 0.96 | CNR2 (0.64) | CNR1CNR2CYP3A4MAPTALOX15 | |
| SCHEMBL4653103 | 0.93 | CNR1 (0.67) | CNR1CNR2CYP3A4MAPTALOX15 | |
| SCHEMBL4650719 | 0.85 | ESR1 (0.51) | CNR1CNR2CYP3A4MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL7936198 | 0.84 | ESR1 (0.50) | CNR1CNR2CYP3A4MAPTALOX15 | |
| SCHEMBL4651950 | 0.84 | CNR2 (0.65) | CNR1CNR2CYP3A4MAPTALOX15 | |
| SCHEMBL4651826 | 0.82 | ESR1 (0.60) | CNR1CNR2CYP3A4MAPTALOX15 | |
| SCHEMBL720445 | 0.81 | SLC2A1 (0.63) | CNR1CNR2CYP3A4MAPTALOX15 | |
| SCHEMBL6746977 | 0.81 | CNR2 (0.82) | CNR1CNR2CYP3A4MAPTALOX15 | |
| SCHEMBL7640834 | 0.80 | CNR2 (0.74) | CNR1CNR2CYP3A4MAPTALOX15 | |
| SCHEMBL6751759 | 0.77 | CYP3A4 (0.43) | CNR1CNR2CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707852-A2 | Bicyclic bradykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | claimed |