Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.51 |
| ▸ | ENPP3 | O14638 | 6/20 | 0.45 |
| ▸ | ENPP1 | P22413 | 6/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056354 | 0.96 | ESR1 (0.54) | ESR1ESR2ABCC1STS | |
| SCHEMBL8589095 | 0.94 | ESR1 (0.60) | ESR1ESR2ABCC1STS | |
| SCHEMBL7942841 | 0.83 | ESR1 (0.52) | ESR1ESR2ENPP3ENPP1ABCC1 | |
| SCHEMBL7944330 | 0.81 | ESR1 (0.51) | ESR1ESR2ENPP3ENPP1ABCC1 | |
| SCHEMBL7944288 | 0.81 | ESR1 (0.51) | ESR1ESR2ENPP3ENPP1ABCC1 | |
| SCHEMBL4651812 | 0.80 | ESR1 (0.71) | ESR1ESR2ENPP3ENPP1ABCC1 | |
| SCHEMBL7942816 | 0.80 | ESR1 (0.50) | ESR1ESR2ENPP3ENPP1ABCC1 | |
| SCHEMBL4651711 | 0.79 | ESR1 (0.69) | ESR1ESR2ENPP3ENPP1ABCC1 | |
| SCHEMBL2057145 | 0.79 | ESR1 (0.64) | ESR1ESR2 | |
| SCHEMBL8042270 | 0.79 | ESR1 (0.69) | ESR1ESR2ENPP3ENPP1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716854-A2 | Compositions for inhibiting neuropeptide y receptors | ELI LILLY AND COMPANY (US) | 1996-06-19 | — | — | EP | disclosed |
| EP-0709090-A2 | Compositions for treating resistant tumors | ELI LILLY AND COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0707852-A2 | Bicyclic bradykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |