Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9006395 | 0.83 | USP2 (0.65) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6965437 | 0.82 | USP2 (0.64) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9536593 | 0.82 | USP2 (0.59) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9536587 | 0.82 | USP2 (0.59) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9534501 | 0.81 | USP2 (0.61) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9534489 | 0.81 | USP2 (0.61) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5711299 | 0.81 | USP2 (0.63) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3184957 | 0.81 | USP2 (0.63) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8842431 | 0.81 | USP2 (0.63) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4291455 | 0.81 | USP2 (0.63) | USP2PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530506-B1 | Optically active omega-halogen-2-amino alkanoic acids derivatives, process for their preparation and their use for the preparation of optically active phosphor-containing alpha-aminoacids | HOECHST SCHERING AGREVO GMBH (DE) | 1996-05-01 | — | — | EP | disclosed |