Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978813 | 0.90 | ACACB (0.56) | ACACBFFAR1FFAR4HTR2ACHRM2 | |
| SCHEMBL8978935 | 0.89 | HSD17B10 (0.45) | ACACBHSD17B10TSHRFFAR1FFAR4 | |
| SCHEMBL7858601 | 0.89 | FFAR1 (0.51) | ACACBHSD17B10TSHRFFAR1FFAR4 | |
| SCHEMBL7858590 | 0.87 | FFAR1 (0.50) | HSD17B10TSHRFFAR1FFAR4HTR2A | |
| SCHEMBL8979094 | 0.87 | HSD17B10 (0.48) | ACACBHSD17B10TSHRFFAR1FFAR4 | |
| SCHEMBL8979123 | 0.87 | HSD17B10 (0.48) | ACACBHSD17B10TSHRFFAR1FFAR4 | |
| SCHEMBL8978772 | 0.87 | HSD17B10 (0.48) | ACACBHSD17B10TSHRFFAR1FFAR4 | |
| SCHEMBL8978895 | 0.87 | HSD17B10 (0.48) | ACACBHSD17B10TSHRFFAR1FFAR4 | |
| SCHEMBL8979169 | 0.87 | HSD17B10 (0.48) | ACACBHSD17B10TSHRFFAR1FFAR4 | |
| SCHEMBL8978968 | 0.87 | HSD17B10 (0.48) | ACACBHSD17B10TSHRFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581272-B1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORP (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5356558-A | Compatibility, high speed response | SEIKO EPSON CORPORATION (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0581272-A1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORPORATION (JP) | 1994-02-02 | — | — | EP | disclosed |