Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 13/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31633771 | 1.00 | ACACB (0.39) | ACACBFFAR1FFAR4CYP1A2CYP2D6 | |
| SCHEMBL8978862 | 0.92 | ACACB (0.38) | ACACBFFAR1FFAR4CYP1A2CYP2D6 | |
| SCHEMBL8978893 | 0.91 | FFAR1 (0.43) | ACACBFFAR1FFAR4CHRM2S1PR1 | |
| SCHEMBL19403081 | 0.89 | HSD17B10 (0.43) | ACACBFFAR1FFAR4CHRM2 | |
| SCHEMBL15430817 | 0.89 | FFAR1 (0.43) | ACACBFFAR1FFAR4CYP1A2CYP2D6 | |
| SCHEMBL19384848 | 0.88 | ACACB (0.41) | ACACBFFAR1FFAR4CYP1A2CYP2D6 | |
| SCHEMBL8979104 | 0.86 | FFAR1 (0.40) | ACACBFFAR1FFAR4CHRM2S1PR1 | |
| SCHEMBL8978969 | 0.85 | FFAR1 (0.46) | ACACBFFAR1FFAR4CYP1A2CHRM2 | |
| SCHEMBL31350274 | 0.85 | ACACB (0.43) | ACACBFFAR1FFAR4CHRM2S1PR1 | |
| SCHEMBL8978759 | 0.85 | PTPN11 (0.40) | ACACBFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581272-B1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORP (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5356558-A | Compatibility, high speed response | SEIKO EPSON CORPORATION (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0581272-A1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORPORATION (JP) | 1994-02-02 | — | — | EP | disclosed |