⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9875272 | 0.96 | — | — | |
| SCHEMBL5571937 | 0.74 | — | — | |
| SCHEMBL18636650 | 0.74 | — | — | |
| SCHEMBL14498615 | 0.74 | — | — | |
| SCHEMBL20079296 | 0.72 | — | — | |
| SCHEMBL25141588 | 0.72 | — | — | |
| SCHEMBL22187123 | 0.72 | — | — | |
| SCHEMBL20502626 | 0.72 | — | — | |
| SCHEMBL21730034 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL25237762 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 181 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260049101-A1 | TOPICAL TREATMENT OF SKIN CANCER USING OLIGOPEPTIDES | BACOBA AG (CH) | 2026-02-19 | — | — | US | disclosed |
| US-20250346564-A1 | INHIBITORS OF PARG | ARASE THERAPEUTICS INC (US) | 2025-11-13 | — | — | US | disclosed |
| US-20250073204-A1 | ANALOGS OF CYCLOBENZAPRINE AND AMITRYPTILENE | TONIX Pharmaceuticals Holding Corp (US) | 2025-03-06 | — | — | US | disclosed |
| US-12227484-B2 | Inhibitors of PARG | ARASE THERAPEUTICS INC. (US) | 2025-02-18 | — | — | US | disclosed |
| EP-4479387-A1 | INHIBITORS OF PARG | ARase Therapeutics Inc. (US) | 2024-12-25 | — | — | EP | disclosed |
| US-12156864-B2 | Analogs of cyclobenzaprine and amitryptilene | TONIX Pharmaceuticals Holding Corp (US) | 2024-12-03 | — | — | US | disclosed |
| CN-119013261-A | Inhibitors of PARG | 雅瑞斯医疗公司 | 2024-11-22 | — | — | CN | disclosed |
| EP-4460295-A1 | MEK IMMUNE ONCOLOGY INHIBITORS AND THERAPEUTIC USES THEREOF | Immuneering Corporation (US) | 2024-11-13 | — | — | EP | disclosed |
| US-20240174714-A1 | TREATMENT OF SKIN DISORDERS | BACOBA AG (CH) | 2024-05-30 | — | — | US | disclosed |
| WO-2024102859-A1 | MEK IMMUNE ONCOLOGY INHIBITORS AND THERAPEUTIC USES THEREOF | IMMUNEERING CORPORATION (US) | 2024-05-16 | — | — | WO | disclosed |
| US-20110053912-A1 | PYRIMIDINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20110053912-A1 | PYRIMIDINE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2011-03-03 | — | — | US | disclosed |
| WO-2010113834-A1 | PYRIMIDINE COMPOUND | アステラス製薬株式会社 (JP) | 2010-10-07 | — | — | WO | disclosed |
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |
| US-20090143377-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | ELI LILLY AND COMPANY | 2009-06-04 | — | — | US | disclosed |
| US-20090069298-A1 | Pyrazolo[1,5-A]Pyrimidine Compounds | TANABE SEIYAKU CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20090069298-A1 | Pyrazolo[1,5-A]Pyrimidine Compounds | TANABE SEIYAKU CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| WO-2009016460-A2 | PYRAZOLE COMPOUNDS AND THEIR USE AS RAF INHIBITORS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| WO-2008071646-A1 | NEW PYRIDAZINE DERIVATIVES WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-19 | — | — | WO | disclosed |
| EP-0127365-A2 | Heat pumps | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-05 | — | — | EP | disclosed |